African-American
Anti-Slavery Collection - 600 volumes on the history of the Anti-Slavery movement in the United States. (Central Library - Grosvenor Rare Book Room)
Center for Afro-American History & Research ( Merriweather,Frank E., Jr.)
Art, Illustrations, Pictures
Framed art prints for loan. (Orchard Park Public Library)
Etchings of local artist William J. Schwanekamp and woodcuts of local artist J.J. Lankes (Central Library - Grosvenor Rare Book Room)
Illustrated Books Collection - includes many important 19th century color plate books, the most famous of which is John James Audubon's The Birds of America. (Central Library - Grosvenor Rare Book Room)
Niagara Falls Prints (300) (Central Library - Grosvenor Rare Book Room)
Health
CHADD - Children and Adults with Attention Deficit Disorder (East Aurora Library)
Languages
Russian language materials (Crane Branch Library)
Spanish Language Resource Center (Niagara Branch Library)
Vietnamese language materials (Niagara Branch Library)
Literature
American Literature Collection - 2,000 volumes of American literature, including original works by Walt Whitman, Edgar Allen Poe, Ralph Waldo Emerson, Benjamin Franklin, Henry James, and James Fenimore Cooper. (Central Library - Grosvenor Rare Book Room)
English Literature Collection - 1,000 volumes of English literature, including the four Shakespeare folios of 1623, 1632, 1664, and 1685. (Central Library - Grosvenor Rare Book Room)
Local History, Records, Newspapers
Amherst - History and documents
Amherst Main Library at Audubon
Clearfield Branch Library
Eggertsville-Snyder Branch Library
Williamsville Branch Library
Amherst Bee on microfilm since March 1879 (Williamsville Branch Library)
Buffalo/Western New York - Buffalo News on microfilm, January 1989-present (Kenmore Branch Library)
Local History Collection - 1,300 volumes including many rare early Western New York imprints and exceptional works relating to the history of the Niagara Frontier (Central Library - Grosvenor Rare Book Room)
East Aurora - History (East Aurora Library)
Elma - History (Elma Public Library)
Grand Island - History, including complete runs of the Grand Island Record and the Grand Island Dispatch newspapers (Grand Island Memorial Library)
Hamburg - History, including the Hamburg Sun and Erie County Independent, 1875-present (Hamburg Branch Library)
Lackawanna - History, including Lackawanna Leader, 1936-1980, Front Page newspaper, 1979-present, and Steel Plant Museum (Lackawanna Public Library)
Lancaster - History (Lancaster Public Library)
Marilla - History (Marilla Free Library)
North Collins - History (North Collins Memorial Library)
City of Tonawanda - FUSRAP Administrative Record for the Tonawanda Sites, New York (City of Tonawanda Public Library)
Williamsville - History, including the Amherst Bee on microfilm since March 1879 (Williamsville Branch Library)
Native American
Locally found Native American tools and artifacts. (Alden (Ewell) Free Library)
New York State Law
McKinney's Consolidated Laws of New York, annotated (West Seneca Public Library)
Religion
Bible Collection - a collection of significant editions (Central Library - Grosvenor Rare Book Room)
Shaker Collection - 275 volumes of original writings and hymns. (Central Library - Grosvenor Rare Book Room)
Science, Environment
History of Science and Medicine Collection (Central Library - Grosvenor Rare Book Room)
Milestones of Science (Central Library - Grosvenor Rare Book Room)
West Valley Nuclear Demonstration Collection (Concord Public Library)
United States
Americana Collection - 8,000 volumes with imprints ranging from the 16th century to the present. The collection includes 3,000 early American imprints, the earliest being a 1675 Thanksgiving broadside. (Central Library - Grosvenor Rare Book Room)